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Giants Insider: Bills a threat for Blue even without McCoy

If LeSean McCoy (pictured) misses Sunday's game, the Bills still have Karlos Williams.Lynne Sladky/AP

If LeSean McCoy (pictured) misses Sunday’s game, the Bills still have Karlos Williams.

The Giants defense just may get a break and not have to face an old nemesis on Sunday afternoon. But that doesn’t mean its job will be any easier.

According to Bills coach Rex Ryan, there is a “real possibility” that running back LeSean McCoy will sit out this week as he continues to recover from a hamstring injury. During his six seasons with the Eagles, McCoy routinely tormented the Giants with his speedy end-to-end rushing style, but he is off to a slow start this year, with 146 rushing yards in three games.

Not that the Giants can disregard the Bills’ run game, as rookie backup Karlos Williams is equally dangerous. Williams actually leads the Bills with three rushing touchdowns and 186 yards on the ground.

“It won’t change,” Coughlin said of Buffalo’s top-ranked rushing attack. “We know LeSean very well, and he’s an excellent runner, always had significant days against us. But Williams is a powerful guy, a bigger guy, a slam-it-up-in-there, north-and-south guy. He has the speed to get outside, he’s 4.48. Got to defend it all.”

Meanwhile, in more potentially good news for the Giants, Ryan made it sound as if wide receiver Sammy Watkins (calf) will sit, too.

FELLS DOWN

Tight end Daniel Fells did not practice for the Giants on Wednesday. He is still dealing with the ankle injury that has nagged him since Week 2. Fellow tight end Jerome Cunningham (knee) also sat out.

If Fells, the team’s best blocking tight end, can’t play, the Giants could end up facing Buffalo with just one healthy player at the position, and in run situations they might need to use an extra offensive lineman at the position. Coughlin said the team has “prepared that way before,” although he added, “I still think Fells will make it.”

IN AND OUT

DE Robert Ayers (hamstring), RB Orleans Darkwa (knee), LT Ereck Flowers (ankle), DT Markus Kuhn (knee) and DE Owa Odighizuwa (foot) were limited. . . . CB Dominique Rodgers-Cromartie (concussion) practiced fully. . . . Bills WR Percy Harvin (hip) did not practice, although he typically misses at least one practice session per week.

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